General Cell Lines and Cell Cultures
Eurofins Discoverx ChemiScreen D1 Dopamine Receptor Stable Cell Line, 2 vials. (HTS102C)
The ChemiScreen D1 Dopamine Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. dopamine) based activation of DRD1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses DRD1 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of DRD1, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Cayman Chemical THUNDRTotal MEK1 TRFRET C 96
Sandwich TR-FRET immunoassay for semi-quantitative detection of Total MEK1 in cell lysates
Eurofins Discoverx KILR SKBR3 Cell Pool, 2 vials. (97-1002P018)
The KILR SKBR3 cell pool is a stable, engineered target cell pool, which closely reflects the heterogeneous native protein expression of tumor environments, used to measure direct cell death mediated by immunooncology treatments (e.g. checkpoint modulators, bispecifics, CAR-T, etc.) via Antibody Dependent Cell-mediated Cytotoxicity (ADCC), Complement Dependent Cytotoxicity (CDC), and Antibody Dependent Cell Phagocytosis (ADCP). This product uses EFC technology. The cell pool is a heterogeneous population of SKBR3 cells that overexpress a ProLabel-tagged housekeeping gene. Upon effector cells-mediated cell lysis, ProLabel is released to the media, where EA in the detection kit produces an EFC signal proportional to the level of ProLabel released. This allows for calculation of percent lysis of the KILR cell pool. This stable cell pool is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kilr.
Eurofins Discoverx PrecisION hnAChR α3/β4 Recombinant Stable Cell Line, 2 vials. (CYL3057)
The PrecisION hnAChR α3/β4 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying nAChR α3/β4 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses nAChR α3/β4 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
Biochain Institute Inc Paraffin Tissue Section - Human Adult Normal: Stomach, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Eurofins Discoverx ChemiScreen 5-HT2C Serotonin Receptor Membrane Preparation, 1 vial. (HTS132M)
The ChemiScreen 5-HT2C Serotonin Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of HTR2C surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
ATCC TAU RD P301S FRET BIOSENSOR EM
For-profit Organizations: For every order of this item, you must work directly with the contributor, Washington University in St. Louis to (i) negotiate a research-use license, and/or (ii) have the contributor provide authorization to ATCC to ship this item under your existing license. We cannot ship this item until we receive communication directly from Washington University in St. Louis that we are authorized to ship each order. We are providing the following contact information, but this information may change without notice: Washington University, Office of Technology Management, Attn. Associate Director, Phone: 314-747-0920 Email: otm@dom.wustl.edu. Once ATCC has received authorization from Washington University in St. Louis, your order will be reviewed, and this item will be released for shipment if all requirements are met. If you need assistance with your order, please contact our Customer Care team.
ATCC C4-2B; Prostate Cancer; Human (Homo sapiens)
For-profit Organizations: For every order of this item, you must work directly with the contributor, MD Anderson Cancer Center to (i) negotiate a research-use license, and/or (ii) have the contributor provide authorization to ATCC to ship this item under your existing license. We cannot ship this item until we receive communication directly from MD Anderson Cancer Center that we are authorized to ship each order. We are providing the following contact information, but this information may change without notice: M.D. Anderson Cancer Center, Office of Technology Commercialization Email: researchtools@mdanderson.org. Once ATCC has received authorization from MD Anderson Cancer Center, your order will be reviewed, and this item will be released for shipment if all requirements are met. If you need assistance with your order, please contact our Customer Care team.
ATCC Parabacteroides distasonis
This organism is included in the bioMérieux VITEK 2 - ANC ID Card Quality Control Organism Set
ATCC Streptococcus pyogenes; Strain MGAS 10270; genomic DNA
Genomic DNA isolated from Streptococcus pyogenes strain MGAS 10270. This bacterial strain is also available as ATCC Catalog No. BAA-1063™.
MSC SPI 13-312-4 Ring & Plug Thread Gage Holders & Handles; Type: Pin Gage Handle ; Handle Size: M0 ; Minimum Ring Diameter (Decimal Inch): 0.0610 ; Maximum Ring Diameter (Decimal Inch): 0.2500 ; Material: Aluminum
SPI 13-312-4 Ring & Plug Thread Gage Holders & Handles; Type: Pin Gage Handle ; Handle Size: M0 ; Minimum Ring Diameter (Decimal Inch): 0.0610 ; Maximum Ring Diameter (Decimal Inch): 0.2500 ; Material: Aluminum
Eurofins Discoverx ChemiScreen MC2 Melanocortin Receptor Stable Cell Line, 2 vials. (HTS021C)
The ChemiScreen MC2 Melanocortin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. adrenocorticotropin) based activation of MC2R GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses MC2R alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of MC2R, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC Enterococcus faecalis; Quantitative DNA
ATCC Genuine Nucleics can be used for assay development, verification, validation, monitoring of day-to-day test variation, and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load.
